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Merck
CN

SML1796

阿扎那韦

≥98% (HPLC), HIV protease inhibitor, powder

别名:

1,14-二甲基（3S，8S，9S，12S）-3,12-双（1,1-二甲基乙基）-8-羟基-4,11-二氧代-9-（苯甲基）-6-[[4- （2-吡啶基）苯基]甲基] -2,5,6,10,13-五叠氮丙二酸酯, BMS-232632

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关于此项目

经验公式（希尔记法）:
C38H52N6O7
化学文摘社编号:
198904-31-3
分子量:
704.86
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
MFCD08435966
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100

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产品名称

阿扎那韦, ≥98% (HPLC)

form

powder

InChI

1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,32+/m0/s1

SMILES string

O=C(N[C@@H](C(C)(C)C)C(N[C@H]([C@H](CN(CC1=CC=C(C2=NC=CC=C2)C=C1)NC([C@@H](NC(OC)=O)C(C)(C)C)=O)O)CC3=CC=CC=C3)=O)OC

InChI key

AXRYRYVKAWYZBR-GASGPIRDSA-N

assay

≥98% (HPLC)

optical activity

[α]/D -41 to -49°, c = 0.1 in ethanol

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

−20°C

Quality Level

100

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相关类别

Biochem/physiol Actions

阿扎那韦是一种抗病毒 HIV 蛋白酶抑制剂。

General description

阿扎那韦抑制人免疫缺陷病毒中 gag 和 gag-pol 多蛋白的裂解。它被肝脏中的细胞色素 P450 吸收和代谢。它具有最小的副作用，并且对胰岛素敏感性和血清脂质谱没有影响。

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000186835
0000186834
0000186834
0000186835
0000138102

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