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Merck
CN

SML1853

Kaempferitrin

≥97% (NMR)

别名:

3,7-Bis((6-deoxy-α-L-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Kaempferol 3,7-dirhamnoside, Lespedin, Lespenefril, Lespenephryl

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关于此项目

经验公式（希尔记法）:
C27H30O14
化学文摘社编号:
482-38-2
分子量:
578.52
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD21333499

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产品名称

Kaempferitrin, ≥97% (NMR)

InChI

1S/C27H30O14/c1-9-17(30)20(33)22(35)26(37-9)39-13-7-14(29)16-15(8-13)40-24(11-3-5-12(28)6-4-11)25(19(16)32)41-27-23(36)21(34)18(31)10(2)38-27/h3-10,17-18,20-23,26-31,33-36H,1-2H3/t9-,10-,17-,18-,20+,21+,22+,23+,26-,27-/m0/s1

SMILES string

OC(C=C1)=CC=C1C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(C4=C(O)C=C(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)C=C4O2)=O

InChI key

PUPKKEQDLNREIM-QNSQPKOQSA-N

biological source

(Cinnamomum sp.)

assay

≥97% (NMR)

form

powder

storage condition

desiccated
protect from light

color

white to beige

storage temp.

−20°C

Quality Level

100

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相关类别

Biochem/physiol Actions

Kaempferitrin (Lespenefril) is a naturally-occurring kaempferol glycoside with antimicrobial, antioxidant, and anti-inflammatory activities.
Kaempferitrin is a flavonol glycoside, present in several plants, predominant in Bauhinia. It is known to stimulate insulin signaling pathway and induces glucose uptake, by mediating GLUT4 (glucose transporter 4) translocation to adipocyte membrane.. Kaempferitrin aids in lowering blood glucose level and therefore helps to improve the glycemic condition in diabetic animals.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number
0000463170
0000463170
0000377967
0000377967
0000167194

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Discovery and Development of Antidiabetic Agents from Natural Products, 118-118 (2016)
Julia Cassani et al.
Molecules (Basel, Switzerland), 19(12), 21442-21461 (2014-12-24)
We evaluated the antidepressant-like effect of kaempferitrin (Km) isolated from the plant Justicia spicigera (Asteraceae), which is used in traditional medicine for relieving emotional disorders, such as "la tristeza" (sadness or dysthymia) and "el humor" (mood changes). The actions of
Plants with Anti-Diabetes Mellitus Properties, 88-88 (2016)
Xue-Qin Ma et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 22(13), 1159-1162 (2015-11-26)
Podocarpium podocarpum (DC.), an edible and medicinal plant popularly used for the treatment of bruises and fracture in Chinese folk medicine, has been proved to possess significant antiosteoporotic effect in our latest research. Our study aimed to investigate the in
Kaempferitrin activates the insulin signaling pathway and stimulates secretion of adiponectin in 3T3-L1 adipocytes
Tzeng YM, et al.
European Journal of Pharmacology, 607(1-3), 27-34 (2009)
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