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Merck
CN

SML1853

Sigma-Aldrich

Kaempferitrin

≥97% (NMR)

别名:

3,7-Bis((6-deoxy-α-L-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Kaempferol 3,7-dirhamnoside, Lespedin, Lespenefril, Lespenephryl

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关于此项目

经验公式（希尔记法）:
C27H30O14
化学文摘社编号:
482-38-2
分子量:
578.52
MDL编号:
MFCD21333499
UNSPSC代码:
12352200
NACRES:
NA.77

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生物来源

(Cinnamomum sp.)

质量水平

100

方案

≥97% (NMR)

表单

powder

储存条件

desiccated
protect from light

颜色

white to beige

储存温度

−20°C

SMILES字符串

OC(C=C1)=CC=C1C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(C4=C(O)C=C(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)C=C4O2)=O

InChI

1S/C27H30O14/c1-9-17(30)20(33)22(35)26(37-9)39-13-7-14(29)16-15(8-13)40-24(11-3-5-12(28)6-4-11)25(19(16)32)41-27-23(36)21(34)18(31)10(2)38-27/h3-10,17-18,20-23,26-31,33-36H,1-2H3/t9-,10-,17-,18-,20+,21+,22+,23+,26-,27-/m0/s1

InChI key

PUPKKEQDLNREIM-QNSQPKOQSA-N

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相关类别

生化/生理作用

Kaempferitrin (Lespenefril) is a naturally-occurring kaempferol glycoside with antimicrobial, antioxidant, and anti-inflammatory activities.
Kaempferitrin is a flavonol glycoside, present in several plants, predominant in Bauhinia. It is known to stimulate insulin signaling pathway and induces glucose uptake, by mediating GLUT4 (glucose transporter 4) translocation to adipocyte membrane.. Kaempferitrin aids in lowering blood glucose level and therefore helps to improve the glycemic condition in diabetic animals.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000463170
0000463170
0000377967
0000377967
0000167194

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Medicinal and Aromatic Plants of South America: Brazil, 142-142 (2018)
Kaempferitrin activates the insulin signaling pathway and stimulates secretion of adiponectin in 3T3-L1 adipocytes
Tzeng YM, et al.
European Journal of Pharmacology, 607(1-3), 27-34 (2009)
Plants with Anti-Diabetes Mellitus Properties, 88-88 (2016)
Julia Cassani et al.
Molecules (Basel, Switzerland), 19(12), 21442-21461 (2014-12-24)
We evaluated the antidepressant-like effect of kaempferitrin (Km) isolated from the plant Justicia spicigera (Asteraceae), which is used in traditional medicine for relieving emotional disorders, such as "la tristeza" (sadness or dysthymia) and "el humor" (mood changes). The actions of
Discovery and Development of Antidiabetic Agents from Natural Products, 118-118 (2016)
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