SML1885
米托坦
≥98% (HPLC)
别名:
1-(2-氯苯基)-1-(4-氯苯基)-2,2-二氯乙烷, 2,4′-DDD, o,p′-DDD
登录并加购，请在购物车里查看协议价、货期和发货地。
选择规格
变更视图
关于此项目
经验公式（希尔记法）:
C14H10Cl4
化学文摘社编号:
分子量:
320.04
UNSPSC Code:
12352200
NACRES:
NA.77
EC Number:
200-166-6
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
ClC1=C(C(C(Cl)Cl)C2=CC=C(Cl)C=C2)C=CC=C1
InChI
1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H
InChI key
JWBOIMRXGHLCPP-UHFFFAOYSA-N
Biochem/physiol Actions
Mitotane is a selective inhibitor of sterol-Oacyl-transferase 1 (SOAT1), also known as ACAT1, (acyl-coenzyme A cholesterol acyltransferase).
Mitotane is a selective inhibitor of sterol-Oacyl-transferase 1 (SOAT1), also known as ACAT1, (acyl-coenzyme A cholesterol acyltransferase). Mitotane inhibition of SOAT1 in adrenocortical carcinoma cells decreased the formation of cholesteryl esters, which increased free cholesterol levels and caused endoplasmic reticulum (ER) stress, the unfolded protein response, and eventually apoptosis.
Still not finding the right product?
Explore all of our products under 米托坦
signalword
Warning
hcodes
Hazard Classifications
Carc. 2
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable