SML1894
SYP-5
≥98% (HPLC)
别名:
(2E)-1-(5-Hydroxy-2-2-dimethyl-2H-1-benzopyran-6-yl)-3-(2-thienyl)-2-propen-1-one, (E)-1-(5-Hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(thio-phen-2-yl)prop-2-en-1-one
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C18H16O3S
化学文摘社编号:
分子量:
312.38
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=C(C=CC(C)(C)O2)C2=CC=C1C(/C=C/C3=CC=CS3)=O
InChI key
OMVURDVBYIJCOI-FNORWQNLSA-N
Biochem/physiol Actions
SYP-5 is potent and selective inhibitor of HIF-1 activity.
SYP-5 is potent and selective inhibitor of HIF-1 activity that decreases HIF-1α and HIF-1β protein levels under hypoxic condition. SYP-5 inhibits tumor cell migration and invasion, as well as tumor angiogenesis.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Li-Hui Wang et al.
European journal of pharmacology, 791, 560-568 (2016-10-30)
Hypoxia-inducible factor-1 (HIF-1) plays an essential role in carcinogenesis. The overexpression of HIF-1 induced by hypoxia is closely associated with metastasis, poor prognosis and high mortality. In this study, a novel HIF-1 inhibitor SYP-5 was first observed by the luciferase
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML1894-5MG | 04061832639222 |
| SML1894-25MG | 04061832639215 |