SML1926
GAT211
≥98% (HPLC)
别名:
3-(2-Nitro-1-phenylethyl)-2-phenyl-1H-indole
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关于此项目
经验公式（希尔记法）:
C22H18N2O2
化学文摘社编号:
分子量:
342.39
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
InChI
1S/C22H18N2O2/c25-24(26)15-19(16-9-3-1-4-10-16)21-18-13-7-8-14-20(18)23-22(21)17-11-5-2-6-12-17/h1-14,19,23H,15H2
InChI key
OHZDCJJHWPHZJD-UHFFFAOYSA-N
SMILES string
O=[N+]([O-])CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3)NC4=CC=CC=C42
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
GAT211 is a positive allosteric modulator (PAM) of cannabinoid CB1 receptor signaling.
GAT211 is a positive allosteric modulator (PAM) of cannabinoid CB1 receptor signaling. GAT211 was found to amplify the therapeutic effect of endocannabinoids without the negative side effects of psychoactivity or tolerance. GAT211 caused a CB1-dependent suppression of paclitaxel-induced mechanical and cold allodynia with no sign of tolerance over 19 days of administration.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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