SML1959
GA3-AM
≥95% (HPLC)
别名:
(1α,2β,4aα,4bβ,10β)-2,4a,7-三羟基-1-甲基-8-亚甲基赤霉-3-烯-1,10-二羧酸1,4a-内酯乙酰氧基甲基酯, 赤霉素乙酰氧基甲基酯, （1S，2S，4aR，4bR，7S，9aS，10S，10aR）-1,2,4b，5,6,7,8,9,10,10a-十氢-2,7-二羟基-1-甲基- 8-亚甲基-13-氧代-4a，1-（环氧甲氧基）-7,9a-甲氧基苯[a]]烯-10-乙酸（乙酰氧基）甲酯
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
Quality Level
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
Biochem/physiol Actions
GA3-AM是植物激素赤霉素的细胞可渗透类似物，可充当化学二聚剂或二聚体化学诱导剂。Ga3和雷帕霉素化学诱导的二聚系统是正交的。GA3-AM已与雷帕霉素二聚化系统和CRISPR/Cas9激活剂一起用于时间上控制CRISPR/Cas9激活剂的功能，从而实现了多个基因的时间调控。
植物激素赤霉素的细胞渗透性类似物，起化学二聚剂作用
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Zehua Bao et al.
ACS synthetic biology, 6(4), 686-693 (2017-01-06)
The concerted action of multiple genes in a time-dependent manner controls complex cellular phenotypes, yet the temporal regulation of gene expressions is restricted on a single-gene level, which limits our ability to control higher-order gene networks and understand the consequences
Takafumi Miyamoto et al.
Nature chemical biology, 8(5), 465-470 (2012-03-27)
Using a newly synthesized gibberellin analog containing an acetoxymethyl group (GA(3)-AM) and its binding proteins, we developed an efficient chemically inducible dimerization (CID) system that is completely orthogonal to existing rapamycin-mediated protein dimerization. Combining the two systems should allow applications
Shameika R Wilmington et al.
PloS one, 11(4), e0152679-e0152679 (2016-04-05)
A common way to study protein function is to deplete the protein of interest from cells and observe the response. Traditional methods involve disrupting gene expression but these techniques are only effective against newly synthesized proteins and leave previously existing
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML1959-10MG | 04061832926735 |
| SML1959-50MG | 04061832926742 |