SML1962
IWP-O1
≥98% (HPLC)
别名:
IWP-O1, 5-Phenyl-N-(5-phenylpyridin-2-yl)-4-(pyridin-4-yl)-1H-1,2,3-triazol-1-acetamide, IWP-01
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关于此项目
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 25 mg/mL, clear
storage temp.
2-8°C
SMILES string
[n]3(nnc(c3c5ccccc5)c4ccncc4)CC(=O)Nc1ncc(cc1)c2ccccc2
InChI key
GYYDQHBKIHQHEB-UHFFFAOYSA-N
Biochem/physiol Actions
IWP-O1 is an inhibitor of Porcupine (Porcn), an acyl (palmitoyl) transferase essential for secretion of Wnt proteins and involved in both embryonic development and tumor progression. IWP-O1 has good metabolic stability and is extremely potent, exhibiting an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling.
Porcn Inhibitor
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML1962-5MG | 04061832639406 |
| SML1962-25MG | 04061832639390 |
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