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SML1962

IWP-O1

≥98% (HPLC)

别名:

IWP-O1, 5-Phenyl-N-(5-phenylpyridin-2-yl)-4-(pyridin-4-yl)-1H-1,2,3-triazol-1-acetamide, IWP-01

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关于此项目

经验公式（希尔记法）:
C26H20N6O
化学文摘社编号:
2074607-48-8
分子量:
432.48
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 25 mg/mL, clear

storage temp.

2-8°C

SMILES string

[n]3(nnc(c3c5ccccc5)c4ccncc4)CC(=O)Nc1ncc(cc1)c2ccccc2

InChI key

GYYDQHBKIHQHEB-UHFFFAOYSA-N

Biochem/physiol Actions

IWP-O1 is an inhibitor of Porcupine (Porcn), an acyl (palmitoyl) transferase essential for secretion of Wnt proteins and involved in both embryonic development and tumor progression. IWP-O1 has good metabolic stability and is extremely potent, exhibiting an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling.
Porcn Inhibitor

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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