方案
≥98% (HPLC)
表单
powder
颜色
white to beige
储存温度
2-8°C
SMILES字符串
O[C@@H]1[C@@H]([C@@H](O)C2=CC=CC=C2)O[C@@H](N3C(N=CN=C4N)=C4C=C3)[C@@H]1O
InChI key
WWOOWAHTEXIWBO-CNUKPYSBSA-N
生化/生理作用
LLY-284 is the less potent diastereomer of the potent SAM-competitive PRMT5 inhibitor LLY-283 (IC50 = 20 nM against PRMT5-catalyzed methylation of an H4R3-derived peptide substrate) and an ideal control compound for cellular studies. For characterization details of the active probe, LLY-283, please visit the LLY-283 probe summary on the Structural Genomics Consortium (SGC) website.
LLY-283, the active probe, is available from Sigma. To learn more about and purchase LLY-283, click here.
To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
LLY-283, the active probe, is available from Sigma. To learn more about and purchase LLY-283, click here.
To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
Less potent diastereomer and control compound for the potent and selective SAM-competitive PRMT5 inhibitor LLY-283.
特点和优势
LLY-284 is a negative control for LLY-283, an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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