SML1992
FM-479
≥98% (HPLC)
别名:
(E)-2-Cyano-3-(5-(1-cyclohexyl-6-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide, 2-Cyano-3-(5-(1-cyclohexyl-6-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide, FM-381 Inactive Control
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
yellow to orange
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
CN(C(/C(C#N)=C/C(O1)=CC=C1C2=NC3=CN=C(N(C)C=C4)C4=C3N2C5CCCCC5)=O)C
InChI
1S/C25H26N6O2/c1-29(2)25(32)16(14-26)13-18-9-10-21(33-18)24-28-20-15-27-23-19(11-12-30(23)3)22(20)31(24)17-7-5-4-6-8-17/h9-13,15,17H,4-8H2,1-3H3/b16-13+
InChI key
RPIGHLXKDWUGDT-DTQAZKPQSA-N
Biochem/physiol Actions
FM-479 is an FM-381 structural analog that exhibits no inhibitory potency against JAK3 or other kinases when used at the FM-381 effective dosing range of 100-300 nM. For characterization details of the active probe, FM-381, please visit the FM-381 probe summary on the Structural Genomics Consortium (SGC) website.
FM-381, the active probe, is available from Sigma. To learn more about and purchase FM-381, click here.
To learn about other SGC chemical probes, visit sigma.com/sgc
FM-381, the active probe, is available from Sigma. To learn more about and purchase FM-381, click here.
To learn about other SGC chemical probes, visit sigma.com/sgc
Inactive FM-381 structural analog.
Features and Benefits
FM-479 is a negative control for FM-381, a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable