SML2036
Gigantol
≥98% (HPLC)
别名:
5-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol, CID 3085362
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关于此项目
经验公式（希尔记法）:
C16H18O4
化学文摘社编号:
分子量:
274.31
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
oil
产品名称
Gigantol, ≥98% (HPLC)
SMILES string
O(C)c1c(cc(cc1)CCc2cc(cc(c2)O)OC)O
InChI
1S/C16H18O4/c1-19-14-8-12(7-13(17)10-14)4-3-11-5-6-16(20-2)15(18)9-11/h5-10,17-18H,3-4H2,1-2H3
InChI key
SDXKZPQOVUDXIY-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
oil
color
colorless to light brown
storage temp.
2-8°C
Biochem/physiol Actions
Gigantol is a bibenzyl compound isolated from Dendrobium orchids (Dendrobium aphyllum, Dendrobium draconis, Dendrobium aurantiacum, etc.) that exhibits potent cytotoxic activity against several cancer cell lines. It inhibits the migratory behavior of non-small cell lung cancer cells. Gigantol inhibits galactose-induced formation of cataracts through repression of the gene expression and activity of AR and iNOS.
potent cytotoxic agent isolated from Dendrobium orchids.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Pornprom Klongkumnuankarn et al.
Evidence-based complementary and alternative medicine : eCAM, 2015, 350410-350410 (2015-02-17)
Chromatographic separation of a methanol extract prepared from the whole plant of Dendrobium brymerianum led to the isolation of eight phenolic compounds. Among the isolated compounds (1-8), moscatilin (1), gigantol (3), lusianthridin (4), and dendroflorin (6) showed appreciable cytotoxicity against
Huanhuan Chen et al.
Oncology reports, 37(2), 865-870 (2016-12-14)
Gigantol is a phenolic substance extracted from plants in the genus Dendrobium and used in traditional Chinese medicine. In the present study, we aimed to investigate the growth inhibition and apoptotic effects of gigantol on human liver cancer cells through
Sopanya Charoenrungruang et al.
Journal of natural products, 77(6), 1359-1366 (2014-05-23)
Lung cancer is one of the most common causes of cancer death due to its high metastasis potential. The process of cancer migration is an early step that is required for successful metastasis. The discovery and development of natural compounds
Napachanok Mongkoldhumrongkul Swainson et al.
Heliyon, 9(9), e20197-e20197 (2023-10-09)
Orchidaceae are diverse plants whose bioactive compounds have various biological activities. New hybrids of Dendrobium have been generated to gain characteristics shared with their ancestors. Dendrobium Pearl Vera (designated as DH) is derived from parents used for dermatological treatments and
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