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Merck
CN

SML2046

ARM390

≥98% (HPLC)

别名:

AR-M 1000390, N,N-Diethyl-4-(phenyl-4-piperidinylidenemethyl)benzamide

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关于此项目

经验公式(希尔记法):
C23H28N2O
化学文摘社编号:
分子量:
348.48
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

O=C(C1=CC=C(C(C2=CC=CC=C2)=C3CCNCC3)C=C1)N(CC)CC

InChI

1S/C23H28N2O/c1-3-25(4-2)23(26)21-12-10-19(11-13-21)22(18-8-6-5-7-9-18)20-14-16-24-17-15-20/h5-13,24H,3-4,14-17H2,1-2H3

InChI key

SMUGAZNLKPFBSB-UHFFFAOYSA-N

Biochem/physiol Actions

ARM390 in a δ-selective opioid receptor agonist derivative of SNC80. ARM390 leads to very low levels of receptor internalization, and does not induce acute desensitization of analgesic response compared to SNC80. ARM390 preferentially recruits arrestin 3 to the delta opioid receptor in mice.
low-internalizing δ opioid receptor agonist


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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