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Merck
CN

SML2107

Sigma-Aldrich

Tulathromycin A

≥95% (HPLC), powder, macrolide antibiotic

别名:

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-a-L-ribo-hexopyranosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one, CP-472295

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关于此项目

经验公式（希尔记法）:
C41H79N3O12
化学文摘社编号:
217500-96-4
分子量:
806.08
MDL编号:
MFCD09838804
UNSPSC代码:
12352200
NACRES:
NA.77

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产品名称

Tulathromycin A, ≥95% (HPLC)

方案

≥95% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

储存温度

−20°C

SMILES字符串

C[C@@]([C@H](OC([C@@H]([C@H]1O[C@]2([H])O[C@@H](C)[C@@](O)(CNCCC)[C@@](C2)(OC)C)C)=O)CC)([C@@H]([C@H](NC[C@H](C)C[C@]([C@@H]([C@H]1C)O[C@]3([H])O[C@H](C)C[C@H](N(C)C)[C@H]3O)(O)C)C)O)O

InChI

1S/C41H79N3O12/c1-15-17-42-22-41(50)28(8)53-31(20-39(41,10)51-14)55-33-25(5)35(56-37-32(45)29(44(12)13)18-24(4)52-37)38(9,48)19-23(3)21-43-27(7)34(46)40(11,49)30(16-2)54-36(47)26(33)6/h23-35,37,42-43,45-46,48-50H,15-22H2,1-14H3/t23-,24-,25+,26-,27-,28+,29+,30-,31+,32-,33+,34-,35-,37+,38-,39-,40-,41+/m1/s1

InChI key

GUARTUJKFNAVIK-QPTWMBCESA-N

相关类别

生化/生理作用

Macrolide antibiotic that inhibits bacterial protein synthesis
Tulathromycin A is a macrolide antibiotic. It binds to the subunit 50S of the bacterial ribosome, interfering with bacterial protein synthesis.
Tulathromycin is a triamilide antimicrobial, which is structurally similar to the di-basic azalide antibiotic azithromycin. It is used to treat bovine and swine bacterial respiratory diseases.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H317,H319,H412

危险分类

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000502809
0000502811
0000502811
0000502809
0000445617

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Nigel A Evans
Veterinary therapeutics : research in applied veterinary medicine, 6(2), 83-95 (2005-08-12)
Tulathromycin is a novel triamilide antimicrobial that has been approved for use in the treatment and prevention of bovine respiratory disease and the treatment of swine respiratory disease in the European Union and the United States. The agent penetrates gram-negative
Diana Gáler et al.
Journal of agricultural and food chemistry, 52(8), 2179-2191 (2004-04-15)
Tulathromycin is a novel member of the triamilide class of antibiotics that was developed as a safe and effective single-dose treatment of bovine and porcine respiratory disease. An accurate and precise analytical method was developed for the extraction and measurement
Tulathromycin: An overview of a new triamilide antimicrobial for livestock respiratory disease
Evans NA, et al.
Veterinary Therapeutics : Research in Applied Veterinary Medicine, 6(2), 83-83 (2005)
Nicolas Villarino et al.
Veterinary journal (London, England : 1997), 198(2), 352-357 (2013-11-26)
Tulathromycin is the first and only member of the triamilide sub-class of macrolides that is used therapeutically and has been registered in more than 30 countries across America, Europe, Oceania and Asia. The discovery of tulathromycin and its registration in
An analytical method for the analysis of tulathromycin, an equilibrating triamilide, in bovine and porcine plasma and lung
Galer D, et al.
Journal of Agricultural and Food Chemistry, 52(8), 2179-2191 (2004)
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