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Merck
CN

SML2110

WOBE437

≥98% (HPLC)

别名:

(2E,4E)-N-[2-(3,4-Dimethoxyphenyl)ethyl]dodeca-2,4-dienamide

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关于此项目

经验公式(希尔记法):
C22H33NO3
化学文摘社编号:
分子量:
359.50
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CCCCCCC/C=C/C=C/C(NCCC1=CC(OC)=C(OC)C=C1)=O

InChI

1S/C22H33NO3/c1-4-5-6-7-8-9-10-11-12-13-22(24)23-17-16-19-14-15-20(25-2)21(18-19)26-3/h10-15,18H,4-9,16-17H2,1-3H3,(H,23,24)/b11-10+,13-12+

InChI key

LAHLFCSEHHJQRN-AQASXUMVSA-N

Biochem/physiol Actions

WOBE437 is a highly potent and selective endocannabinoid transport inhibitor. WOBE437 increases endocannabinoid levels in mice. It exhibits potent anxiolytic, anti-inflammatory, and analgesic effects in mice.
highly potent and selective endocannabinoid transport inhibitor


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Andrea Chicca et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(25), E5006-E5015 (2017-06-07)
The extracellular effects of the endocannabinoids anandamide and 2-arachidonoyl glycerol are terminated by enzymatic hydrolysis after crossing cellular membranes by facilitated diffusion. The lack of potent and selective inhibitors for endocannabinoid transport has prevented the molecular characterization of this process



全球贸易项目编号

货号GTIN
SML2110-25MG04061835368945
SML2110-5MG04061835368952