SML2138
IR415
≥98% (HPLC)
别名:
N-(2,4-Difluorophenyl)-N′-[3-(1H-imidazol-1-yl)propyl]-thiourea
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关于此项目
经验公式（希尔记法）:
C13H14F2N4S
化学文摘社编号:
分子量:
296.34
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
InChI
1S/C13H14F2N4S/c14-10-2-3-12(11(15)8-10)18-13(20)17-4-1-6-19-7-5-16-9-19/h2-3,5,7-9H,1,4,6H2,(H2,17,18,20)
InChI key
KRSBPLFMLHNMPU-UHFFFAOYSA-N
SMILES string
S=C(NC1=C(F)C=C(F)C=C1)NCCCN2C=NC=C2
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
HBx is a viral suppressor of host defenses consisting of RNAi-based silencing of viral genes. It is important for HBV replication and also functions as an RNAi suppressor protein. HBx is considered as emerging target for anti-viral therapy.
selective inhibitor of Hepatitis B Virus X Protein (HBx)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Subhanita Ghosh et al.
The Journal of biological chemistry, 292(30), 12577-12588 (2017-06-07)
Persistent or chronic infection with the hepatitis B virus (HBV) represents one of the most common viral diseases in humans. The hepatitis B virus deploys the hepatitis B virus X protein (HBx) as a suppressor of host defenses consisting of
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