Name: Solifenacin succinate
Brand: SIGMA

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About This Item

经验公式（希尔记法）:

C₂₃H₂₆N₂O₂ · C₄H₆O₄

CAS Number:

242478-38-2

分子量:

480.55

MDL编号:

MFCD00954234

UNSPSC代码:

12352200

NACRES:

NA.77

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质量水平

100

方案

≥98% (HPLC)

表单

powder

旋光性

[α]/D +35 to +45°, c = 1 in H₂O

储存条件

desiccated

颜色

white to beige

溶解性

H₂O: 2 mg/mL, clear

储存温度

2-8°C

SMILES字符串

OC(CCC(O)=O)=O.O=C(O[C@H]1CN2CCC1CC2)N3[C@@H](C4=CC=CC=C4)C5=CC=CC=C5CC3

InChI

1S/C23H26N2O2.C4H6O4/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19;5-3(6)1-2-4(7)8/h1-9,18,21-22H,10-16H2;1-2H2,(H,5,6)(H,7,8)/t21?,22-;/m0./s1

InChI key

RXZMMZZRUPYENV-DZSUWJOWSA-N

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生化/生理作用

Solifenacin succinate (SOL) blocks the cholinergic signals to M3 receptors by inhibiting the muscarinic M3 receptors in the bladder. This action prevents the contractions of the detrusor muscles in the urinary bladder wall, leading to relaxing the bladder as well as decreasing urinary urgency and nocturia. Thus, SOL is a widely used antimuscarinic agent for treating the contraction of the overactive bladder.