SML2169
地芬尼多 盐酸盐
≥98% (HPLC)
别名:
1,1-二苯基-4-(1-哌啶基)-1-丁醇, 戴芬逸多
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关于此项目
经验公式（希尔记法）:
C21H27NO · HCl
化学文摘社编号:
分子量:
345.91
UNSPSC Code:
12352100
NACRES:
NA.77
EC Number:
221-850-0
MDL number:
InChI key
AVZIYZHXZAYGJS-UHFFFAOYSA-N
InChI
1S/C21H27NO.ClH/c23-21(19-11-4-1-5-12-19,20-13-6-2-7-14-20)15-10-18-22-16-8-3-9-17-22;/h1-2,4-7,11-14,23H,3,8-10,15-18H2;1H
SMILES string
Cl.OC(CCCN1CCCCC1)(c2ccccc2)c3ccccc3
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
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Biochem/physiol Actions
Diphenidol is a non-selective muscarinic acetylcholine receptor antagonist. Diphenidol is an antiemetic agent used in the treatment of vomiting and vertigo.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Lin Zhang et al.
Forensic science, medicine, and pathology, 11(4), 570-576 (2015-10-21)
Diphenidol hydrochloride (DPN), a nonphenothiazinic antiemetic agent used primarily in patients with Meniere disease and labyrinthopathies to treat vomiting and vertigo, is considered to be a relatively safe drug. Since it was first approved in the United States in 1967
Yu-Wen Chen et al.
Neuroscience letters, 552, 62-65 (2013-08-07)
Diphenidol has been shown to block voltage-gated Na(+) channels, which are associated with specific types of pain. Here, we evaluated the effects of diphenidol on chronic constriction injury (CCI)-evoked allodynia and expression of tumor necrosis factor-α (TNF-α). A peripheral nerve
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