SML2209
贝那替嗪 盐酸盐
≥98% (HPLC)
别名:
α-羟基-α-苯基苯乙酸 2-(二乙氨基)乙酯, 2-(二乙氨基)乙基二苯乙醇酸酯 盐酸盐, 胃复康
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关于此项目
线性分子式:
(C6H5)2C(OH)CO2CH2CH2N(C2H5)2·HCl
化学文摘社编号:
分子量:
363.88
EC Number:
200-324-4
UNSPSC Code:
12352100
MDL number:
InChI key
ZCEHOOLYWQBGQO-UHFFFAOYSA-N
InChI
1S/C20H25NO3.ClH/c1-3-21(4-2)15-16-24-19(22)20(23,17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5-14,23H,3-4,15-16H2,1-2H3;1H
SMILES string
CCN(CCOC(C(C1=CC=CC=C1)(O)C2=CC=CC=C2)=O)CC.Cl
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
mp
177-179 °C (lit.)
solubility
H2O: 2 mg/mL, clear
storage temp.
2-8°C
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Biochem/physiol Actions
Benactyzine is an anticholinergic and antimuscarinic drug that was used as antidepressant. Benactyzine was discontinued in US due to its ineffectiveness.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Melissa Faria et al.
Archives of toxicology, 91(4), 1891-1901 (2016-09-23)
Acute organophosphorus (OP) intoxication is a worldwide clinical and public health problem. In addition to cholinergic crisis, neurodegeneration and brain damage are hallmarks of the severe form of this toxidrome. Recently, we generated a chemical model of severe acute OP
Trond Myhrer et al.
Neuroscience and biobehavioral reviews, 71, 657-670 (2016-10-25)
The threat of chemical warfare agents like nerve agents requires life saving measures of medical pretreatment combined with treatment after exposure. Pretreatment (pyridostigmine) may cause some side effects in a small number of individuals. A comprehensive research on animals has
Lily Raveh et al.
Toxicology and applied pharmacology, 227(1), 155-162 (2008-03-06)
Sarin, a potent cholinesterase inhibitor, induces an array of toxic effects including convulsions and behavioral impairments. We report here on the protection provided by post-exposure antidotal treatments against a lethal dose of sarin (1.2xLD50) by scopolamine, benactyzine, trihexyphenidyl or caramiphen
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