SML2309
Oxaphenamide
≥98% (HPLC)
别名:
2-Hydroxy-N-(4-hydroxyphenyl)benzamide, 4′-Hydroxysalicylanilide, Osalmide, Oxaphenamide, p-hydroxyphenylsalicylamide
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关于此项目
经验公式（希尔记法）:
C13H11NO3
化学文摘社编号:
分子量:
229.23
UNSPSC Code:
12352200
NACRES:
NA.77
EC Number:
208-385-9
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
N(c2ccc(cc2)O)C(=O)c1c(cccc1)O
InChI
1S/C13H11NO3/c15-10-7-5-9(6-8-10)14-13(17)11-3-1-2-4-12(11)16/h1-8,15-16H,(H,14,17)
InChI key
LGCMKPRGGJRYGM-UHFFFAOYSA-N
Biochem/physiol Actions
Osalmid is a potent inhibitor of ribonucleotide reductase small subunit M2 (RRM2) that potently inhibits HBV DNA and cccDNA synthesis in HepG2.2.15 cells. Osalmid inhibits RR (ribonucleotide reductase) activity in vivo, and exhibits synergistic effect with lamivudine on inactivation mutant HBV strain. Osalmid is a biliation activator (choleretic agent), but a mechanism of this activity remains unknown.
potent inhibitor of ribonucleotide reductase small subunit M2 (RRM2) that potently inhibits HBV DNA and cccDNA synthesis; choleretic agent
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3