方案
≥98% (HPLC)
表单
powder
颜色
white to very dark gray
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
生化/生理作用
potent USP1 inhibitor that induces ID1 degradation, upregulation of p21 and cytoxicity in K562 and other leukemic cell lines
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Helena Mistry et al.
Molecular cancer therapeutics, 12(12), 2651-2662 (2013-10-17)
Inhibitor of DNA binding 1 (ID1) transcription factor is essential for the proliferation and progression of many cancer types, including leukemia. However, the ID1 protein has not yet been therapeutically targeted in leukemia. ID1 is normally polyubiquitinated and degraded by
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