SML2349
BAY-604
≥97% (HPLC)
别名:
(S)-N-Ethyl-1-methyl-4-(3-methylmorpholino)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
方案
≥97% (HPLC)
表单
powder
颜色
white to very dark brown
溶解性
H2O: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
O=C(NCC)C1=CC2=C(N1C)N=CC=C2N3CCOC[C@@H]3C
InChI key
SYYSMZCCSNLTHZ-NSHDSACASA-N
生化/生理作用
BAY-604 is a control probe for BAY-707, an inhibitor of the human 7,8-dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1)
Control probe for BAY-707, an inhibitor of the human 7,8-dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1)
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
Fredrik Rahm et al.
Journal of medicinal chemistry, 61(6), 2533-2551 (2018-02-28)
Recent literature has both suggested and questioned MTH1 as a novel cancer target. BAY-707 was just published as a target validation small molecule probe for assessing the effects of pharmacological inhibition of MTH1 on tumor cell survival, both in vitro
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