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Merck
CN

SML2383

Isosilybin

≥98% (HPLC)

别名:

Isosilybin, mixture of isomers, (2R,3R)-2-[2,3-Dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one, Isosilybinin

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关于此项目

经验公式(希尔记法):
C25H22O10
化学文摘社编号:
分子量:
482.44
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O1C(C(Oc3c1cc(cc3)C4Oc5c(c(cc(c5)O)O)C(=O)C4O)c2cc(c(cc2)O)OC)CO

InChI

1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-18-7-12(3-5-16(18)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3

InChI key

FDQAOULAVFHKBX-UHFFFAOYSA-N

Biochem/physiol Actions

Isosilybin is a diastereoisomeric mixture of flavonolignans isosilybin A and isosilybin B isolated from milk thistle (Silybum marianum) that exhibits hepatoprotective activity. Isosilybin potently inhibits Cytochrome P4502C8 (CYP2C8) activity in human liver microsomes. Also Isosilybin is an activator of PPARγ.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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