SML2386
Cycloguanil hydrochloride
≥95% (HPLC)
别名:
1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine hydrochloride
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经验公式（希尔记法）:
C11H14ClN5 · HCl
化学文摘社编号:
分子量:
288.18
UNSPSC Code:
12352200
MDL number:
NACRES:
NA.21
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated
assay
≥95% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
Clc1ccc(cc1)N2C(NC(=N)NC2=N)(C)C.Cl
InChI
1S/C11H14ClN5.ClH/c1-11(2)16-9(13)15-10(14)17(11)8-5-3-7(12)4-6-8;/h3-6H,1-2H3,(H4,13,14,15,16);1H
InChI key
MOUAPRKJJUXEIE-UHFFFAOYSA-N
Application
Cycloguanil hydrochloride is suitable for use as a positive control in screening Plasmodium falciparum strains in microdilution radioisotope antiplasmodial bioassay. It may also be used as internal standard in high performance liquid chromatography for the quantification of urine and plasma samples.
Biochem/physiol Actions
Cycloguanil is it a potential antimalarial drug. It is hydrophilic in nature. Cycloguanil acts as a substrate for the enzyme organic cation transporter 1 (OCT1).
Cycloguanil, a metabolite of proguanil, is a potent dihydrofolate reductase inhibitor.
Dihydrofolate reductase inhibitor, metabolite of proguanil
警示词
Warning
危险代码
Hazard Classifications
Eye Irrit. 2
存储类别
4.1B - Flammable solid hazardous materials
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable