SML2422
槐果碱
≥95% (HPLC)
别名:
(-)-Sophocarpine, 13,14-Didehydromatridin-15-one, SC
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关于此项目
经验公式（希尔记法）:
C15H22N2O
化学文摘社编号:
分子量:
246.35
UNSPSC Code:
12352200
MDL number:
NACRES:
NA.21
Assay:
≥95% (HPLC)
Form:
powder
biological source
Sophora alopecuroides
assay
≥95% (HPLC)
form
powder
optical activity
[α]/D -26 to -35°, c = 0.5 in ethanol
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
[Br-].N21[C@@H]3[C@@H]([C@@H]4N(C[C@@H]3CCC2)C(=O)C=CC4)CCC1.[H+]
InChI
1S/C15H22N2O.BrH/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14;/h1,7,11-13,15H,2-6,8-10H2;1H/t11-,12+,13+,15-;/m0./s1
InChI key
NBBQEIQEBNYSFK-PUILLJIJSA-N
Biochem/physiol Actions
Sophocarpine is a natural product found to have anti-inflammatory, anti-cancer, and antiviral activity. Sophocarpine was active in an mouse xenograft model. It inhibited growth of head and neck squamous cell carcinomas by downregulation of miR-21 expression. Sophocarpine was also shown to protecs mice from a form of hepatitis by inhibiting the IFNg/STAT1 pathway.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable