SML2502
MF-095
≥98% (HPLC)
别名:
(S)-N-(1-((5-(N-(tert-butyl)sulfamoyl)naphthalen-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)cyclopropanecarboxamide
InChI key
JSNVUWHDPLJARW-QHCPKHFHSA-N
SMILES string
[S](=O)(=O)(NC(C)(C)C)c1c2c(c(ccc2)NC(=O)[C@@H](NC(=O)C4CC4)Cc3ccccc3)ccc1
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
Control probe for USP30 inhibitor MF-094
MF-095 is a control probe for MF-094, which is a potent inhibitor of ubiquitin specific protease 30 (USP30)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Arthur F Kluge et al.
Bioorganic & medicinal chemistry letters, 28(15), 2655-2659 (2018-06-25)
Mitophagy is one of the processes that cells use to maintain overall health. An E3 ligase, parkin, ubiquitinates mitochondrial proteins prior to their degradation by autophagasomes. USP30 is an enzyme that de-ubiquitinates mitochondrial proteins; therefore, inhibiting this enzyme could foster
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