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Merck
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SML2528

K-TMZ

≥98% (HPLC)

别名:

8-Acetyl-3-methylimidazo[5,1-d][1,2,3,5]tetrazin-4(3H)-one

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关于此项目

经验公式（希尔记法）:
C7H7N5O2
化学文摘社编号:
2269482-26-8
分子量:
193.16
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC(C(N=C1)=C2N1C(N(C)N=N2)=O)=O

InChI

1S/C7H7N5O2/c1-4(13)5-6-9-10-11(2)7(14)12(6)3-8-5/h3H,1-2H3

InChI key

QXYCTGXCOQXVRU-UHFFFAOYSA-N

Biochem/physiol Actions

K-TMZ is a more potent, more brain-penetrable, less toxic analog of temozolomide (TMZ). It showed superior activity to TMZ in a mouse model of glioblastoma with significantly less myelotoxicity.
Less toxic analog of temozolomide with more potent anticancer activity

pictograms

Health hazard
GHS08

signalword

Warning

Hazard Classifications

Carc. 2 - Muta. 2 - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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