SML2530
CAY10526
≥98% (HPLC)
别名:
4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxyfuran-2(5H)-one, 4-Benzo[b]thien-2-yl-3-bromo-5-hydroxy-2(5H)-furanone, 4-Benzo[b]thiophen-2-yl-3-bromo-5-hydroxy-5H-furan-2-one
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C1OC(C(C2=CC3=C(S2)C=CC=C3)=C1Br)O
InChI
1S/C12H7BrO3S/c13-10-9(11(14)16-12(10)15)8-5-6-3-1-2-4-7(6)17-8/h1-5,11,14H
InChI key
ICCDILPNCJIDAW-UHFFFAOYSA-N
Biochem/physiol Actions
CAY10526 is a selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) expression. CAY10526 potently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells. CAY10526 significantly suppressed tumor growth and increased apoptosis in melanoma xenografts.
selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) expression that potently inhibits PGE2 production
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable