SML2554
RIPK2 inhibitor 1
≥98% (HPLC)
别名:
3-(Benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]-benzamide, MolPort-016-359-762
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关于此项目
经验公式（希尔记法）:
C25H22N4O2
化学文摘社编号:
分子量:
410.47
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
InChI
1S/C25H22N4O2/c1-17-11-12-20(16-22(17)28-24(30)18-7-4-3-5-8-18)25(31)27-21-10-6-9-19(15-21)23-26-13-14-29(23)2/h3-16H,1-2H3,(H,27,31)(H,28,30)
InChI key
OIIYBZHRYXJCHR-UHFFFAOYSA-N
SMILES string
CC1=CC=C(C(NC2=CC(C3=NC=CN3C)=CC=C2)=O)C=C1NC(C4=CC=CC=C4)=O
assay
≥98% (HPLC)
form
powder
color
white to very dark gray
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
RIPK2 inhibitor 1 is a potent and selective inhibitor of Receptor interacting protein kinase 2 (RIPK2) that potently inhibit NFκB activity and the proliferation of cancer cell lines. RIPK2 inhibitor 1 inhibits intestinal and lung inflammation in rodent models.
potent and selective inhibitor of Receptor interacting protein kinase 2 (RIPK2) that potently inhibit NFκB activity
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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