SML2593
MS0021570
≥98% (HPLC)
别名:
5-(Benzylsulfanyl)-N-methyl-1,3,4-thiadiazol-2-amine, 5-(Benzylthio)-N-methyl-1,3,4-thiadiazol-2-amine, MS 21570, MS0021570_1, N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazadiazol-2-amine
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关于此项目
经验公式（希尔记法）:
C10H11N3S2
化学文摘社编号:
分子量:
237.34
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
SMILES string
[s]1c(nnc1NC)SCc2ccccc2
InChI
1S/C10H11N3S2/c1-11-9-12-13-10(15-9)14-7-8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,11,12)
InChI key
KFLNRVSOQJTXDG-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
GPR171 antagonist
MS0021570 is a potent antagonist of GPR171, a G protein-coupled receptor of BigLEN (b-LEN), which is a neuropeptide derived from proSAAS and involved in regulation of feeding. MS0021570 had a IC50 value of 220 nM. It was shown to block inceases in food intake and to reduce anxiety-like behavior and fear conditioning in mice.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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