产品名称
CW3388, ≥98% (HPLC)
SMILES string
N3(CCCCCCC3)Cc1ccc(cc1)c2ccccc2
InChI key
BTDKOFMWYIXWST-UHFFFAOYSA-N
InChI
1S/C20H25N/c1-2-7-15-21(16-8-3-1)17-18-11-13-20(14-12-18)19-9-5-4-6-10-19/h4-6,9-14H,1-3,7-8,15-17H2
assay
≥98% (HPLC)
form
oil
color
colorless to yellow
storage temp.
2-8°C
Biochem/physiol Actions
CW3388 is a cell active and highly potent enhancer of oligodendrocyte formation. CW3388 potently inhibits the cholesterol biosynthesis enzyme Δ8,7-sterol isomerase (EBP). It promotes myelination in vitro.
cell active and highly potent enhancer of oligodendrocyte formation; inhibitor of Δ8,7-sterol isomerase (EBP)
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Dharmaraja Allimuthu et al.
Cell chemical biology, 26(4), 593-599 (2019-02-19)
Small molecules that promote oligodendrocyte formation have been identified in "drug repurposing" screens to nominate candidate therapeutics for diseases in which myelin is lost, including multiple sclerosis. We recently reported that many such molecules enhance oligodendrocyte formation not by their
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