SML2662
SPA70
≥98% (HPLC), human pregnane X receptor antagonist, powder
别名:
1-(2,5-Dimethoxyphenyl)-4-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-5-methyl-1H-12,3-triazole, LC-1
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关于此项目
经验公式（希尔记法）:
C21H25N3O4S
化学文摘社编号:
分子量:
415.51
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
产品名称
SPA70, ≥98% (HPLC)
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
[S](=O)(=O)(c2nn[n](c2C)c3c(ccc(c3)OC)OC)c1ccc(cc1)C(C)(C)C
InChI key
OIOPHIFJQXHPAF-UHFFFAOYSA-N
Biochem/physiol Actions
SPA70 is a cell penetrant, potent and highly selective human pregnane X receptor (hPXR) antagonist that inhibits hPXR in humanized mouse models. It inhibits hPXR-mediated drug metabolism in in primary human hepatocytes and in mouse models.
cell penetrant, potent and highly selective human pregnane X receptor (hPXR) antagonist that inhibits hPXR in humanized mouse models.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable