Quality Segment
assay
≥98% (HPLC)
form
powder
color
faint yellow to dark orange
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
Biochem/physiol Actions
ES24 is an Eeyarestatin 1 analog that blocks protein translocation in vitro and more effectively enhances Sec61-mediated Ca2+ leakage from Endoplasmic Reticulum (ER). Apparently ES24 keep Sec61 in open position allowing Ca2+ ions to move freely through the aqueous channel present. It causes cell-type-specific Ca2+-dependent cell death.
blocks protein translocation in vitro and effectively enhances Sec61-mediated Ca2+ leakage from Endoplasmic Reticulum (ER).
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable