SML2746
SRS11-92
≥98% (HPLC)
别名:
4-(Cyclohexylamino)-3-[(phenylmethyl)amino]-benzoic acid ethyl ester, Ethyl 3-(benzylamino)-4-(cyclohexylamino)benzoate
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to yellow-brown
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
N(C3CCCCC3)c1c(cc(cc1)C(=O)OCC)NCc2ccccc2
InChI key
VHQAJFNLPQULSV-UHFFFAOYSA-N
Biochem/physiol Actions
SRS11-92 is a cell penetrant and potent inhibitor of ferroptosis that attenuates the cell death associated with frataxin knockdown in healthy human fibroblasts. SRS11-92 protects against cell death in in a brain slice model of Huntington′s disease, an oligodendrocyte model of periventricular leukomalacia, and in isolated kidney proximal tubules model of kidney disfunction.
cell penetrant and potent inhibitor of ferroptosis that attenuates the cell death associated with frataxin knockdown in healthy human fibroblasts
存储类别
11 - Combustible Solids
wgk
WGK 3