SML2818
BAY-207
≥98% (HPLC)
别名:
N-(4-(3-Chlorophenoxy)-3-sulfamoylphenyl)-1-(2-chlorophenyl)cyclopropanecarboxamide
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
[S](=O)(=O)(N)c1c(ccc(c1)NC(=O)C4(CC4)c3c(cccc3)Cl)Oc2cc(ccc2)Cl
InChI
1S/C22H18Cl2N2O4S/c23-14-4-3-5-16(12-14)30-19-9-8-15(13-20(19)31(25,28)29)26-21(27)22(10-11-22)17-6-1-2-7-18(17)24/h1-9,12-13H,10-11H2,(H,26,27)(H2,25,28,29)
InChI key
JXAOITUGCKTSTF-UHFFFAOYSA-N
生化/生理作用
BAY-207 is a negative control for a potent and selective P2X4 antagonist BAY-1797.
negative control for a potent and selective P2X4 antagonist BAY-1797
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
Stefan Werner et al.
Journal of medicinal chemistry, 62(24), 11194-11217 (2019-11-21)
The P2X4 receptor is a ligand-gated ion channel that is expressed on a variety of cell types, especially those involved in inflammatory and immune processes. High-throughput screening led to a new class of P2X4 inhibitors with substantial CYP 3A4 induction
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