SML2843
NS3623
≥98% (HPLC)
别名:
1-(3-Trifluoromethylphenyl)-3-[2-(1H-tetrazol-5-yl)-4-bromophenyl]urea, N-[4-Bromo-2-(2H-tetrazol-5-yl)phenyl]-N′-[3-(trifluoromethyl)phenyl]urea, NS 3623
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关于此项目
经验公式（希尔记法）:
C15H10BrF3N6O
化学文摘社编号:
分子量:
427.18
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
FC(F)(F)c1cc(ccc1)NC(=O)Nc2c(cc(cc2)Br)c3[nH]nnn3
InChI
1S/C15H10BrF3N6O/c16-9-4-5-12(11(7-9)13-22-24-25-23-13)21-14(26)20-10-3-1-2-8(6-10)15(17,18)19/h1-7H,(H2,20,21,26)(H,22,23,24,25)
InChI key
JXPULDIATMTIIN-UHFFFAOYSA-N
Biochem/physiol Actions
NS3623 is a potent and selective activator of KV11.1 (hERG) and KV4.3 channels. It activates the IKr and Ito currents and exhibits antiarrhythmic activity. NS3623 may also act as a partial blocker of KV11.1 channels.
potent and selective activator of KV11.1 (hERG) and KV4.3 channels; antiarrhythmic
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable