SML2879
TCS OX2 29 HCl
≥98% (HPLC)
别名:
(2S)-1-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3,3-dimethyl-2-[(4-pyridinylmethyl)amino]-1-butanone HCl, (2S)-2-(4-Pyridylmethylamino)-1-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)-3,3-dimethylbutan-1-one HCl, TCS OX 229, TCS OX2 29, TCS-OX2-29, TCS-OX229, TCS-orexin 2-29
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C23H31N3O3 · xHCl
化学文摘社编号:
分子量:
397.51 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: ≥2.0 mg/mL, clear
storage temp.
−20°C
SMILES string
N2(CCc3c(cc(c(c3)OC)OC)C2)C(=O)[C@@H](NCc1ccncc1)C(C)(C)C
InChI
1S/C23H31N3O3/c1-23(2,3)21(25-14-16-6-9-24-10-7-16)22(27)26-11-8-17-12-19(28-4)20(29-5)13-18(17)15-26/h6-7,9-10,12-13,21,25H,8,11,14-15H2,1-5H3/t21-/m1/s1
InChI key
COFVZFLCAOUMJT-OAQYLSRUSA-N
Biochem/physiol Actions
A potent and selective orexin 2 receptor antagonist for studying Ox2R physiological functions both in cultures and in mice and rats in vivo.
TCS OX2 29 or TCS-OX2-29 is a potent and selective orexin 2 receptor (Ox2R, Ox2-R, Ox-2-R) antagonist (IC50 = 40 nM/Ox2R, >10 μM/Ox1R) with little potency toward 50 other receptors, ion channels, and transporters tested (<30% inhibition at 10 μM). TCS OX2 29 is widely used for elucidating various physiological functions mediated by Ox2R both in cultures and in mice and rats in vivo.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable