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Merck
CN

SML2987

Cefcapene Pivoxil Hydrochloride Hydrate

≥98% (HPLC)

别名:

Cefcapene Pivoxil Hydrochloride Hydrate, [6R-[6α,7β(Z)]]-3-[[(Aminocarbonyl)oxy]methyl]-7-[[2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester monohydrochloride monohydrate

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关于此项目

经验公式(希尔记法):
C23H29N5O8S2 · xHCl · yH2O
分子量:
567.64 (anhydrous free base basis)
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
Storage condition:
desiccated
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产品名称

Cefcapene Pivoxil Hydrochloride Hydrate, ≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

Cefcapene Pivoxil Hydrochloride Hydrate is an orally available prodrug of third-generation cephalosporin cefcapene that exhibits potent and wide spectrum antibacterial activity against Gram-positive and Gram-negative bacteria, including Staphylococcus aureus.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Masamoto Murakami et al.
Dermatology (Basel, Switzerland), 231(4), 304-311 (2015-10-07)
Pustulosis palmaris et plantaris or palmoplantar pustulosis (PPP) is a refractory pustular eruption of the palms and soles with unknown etiology. In addition to skin lesions, PPP patients may present with severe joint pain and pustulotic arthro-osteitis (PAO), especially of
Przemysław Zalewski et al.
Chromatographia, 76(7-8), 387-391 (2013-04-05)
The stability-indicating LC assay method was developed and validated for quantitative determination of cefcapene pivoxil in the presence of degradation products formed during forced degradation studies. An isocratic RP-HPLC method was developed with a Lichrospher RP-18 (250 mm × 4.6 mm, 5 μm) column and
Xin He et al.
Antimicrobial agents and chemotherapy, 48(7), 2604-2609 (2004-06-25)
The aim of this study was to elucidate the absorption mechanism in Caco-2 and rat intestine models in order to improve the accuracy of prediction of oral absorption of ester prodrugs. Pivampicillin and cefcapene pivoxil hydrochloride (CFPN-PI), ester-type oral antibiotics

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