SML3003
AS3334034
≥98% (HPLC)
别名:
7-Methoxy-6-(2-methylpropane-2-sulfonyl)-N-(4-methyl-1H-pyrazol-3-yl)quinolin-4-amine
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
CC1=CNN=C1NC2=CC=NC3=CC(OC)=C(S(=O)(C(C)(C)C)=O)C=C32
InChI
1S/C18H22N4O3S/c1-11-10-20-22-17(11)21-13-6-7-19-14-9-15(25-5)16(8-12(13)14)26(23,24)18(2,3)4/h6-10H,1-5H3,(H2,19,20,21,22)
InChI key
WCPMUQAUSFXFJE-UHFFFAOYSA-N
Biochem/physiol Actions
AS3334034 is an orally available, potent and selective RIP2 (Receptor-interacting protein kinase 2) inhibitor that exhibits renoprotective effects in uninephrectomized adriamycin-induced CKD (chronic kidney disease) rats. It appears that AS3334034 suppresses the progression of chronic renal failure via an anti-inflammatory effect.
Orally available, potent and selective RIP2 inhibitor that exhibits renoprotective effects
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable