SML3021
ADLumin-1
≥98% (HPLC)
别名:
6-((1E,3E)-4-(4-(dimethylamino)phenyl)buta-1,3-dien-1-yl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one, 6-[4-[4-(Dimethylamino)phenyl]-1,3-butadien-1-yl]-2-methyl-imidazo[1,2-a]pyrazin-3(7H)-one
SMILES string
CN(C1=CC=C(C=C1)/C=C/C=C/C2=CN3C(N=C(C3=O)C)=CN2)C
assay
≥98% (HPLC)
form
powder
color
faint yellow to dark orange
solubility
H2O: 0.1 mg/mL (warmed)
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
ADLumin-1 brain blood barrier penetrant smart chemiluminescence probe for Aβ (amyloid beta) species. Upon binding to Aβ, ADLumin-1 chemiluminescence dramatically increases and its peak shifts from 590 nm to 540 nm. ADLumin-1 is suitable for in vivo dually-amplify signal via chemiluminescence resonance energy transfer (DAS-CRET) with CRANAD-3 a smart NIRF (near infrared fluorescence imaging) probe for Aβs. Apparently both probes bind to Aβ aggregates in close proximity.
brain blood barrier penetrant smart chemiluminescence probe for Aβ (amyloid beta) species
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Jing Yang et al.
Nature communications, 11(1), 4052-4052 (2020-08-15)
Turn-on fluorescence imaging is routinely studied; however, turn-on chemiluminescence has been rarely explored for in vivo imaging. Herein, we report the design and validation of chemiluminescence probe ADLumin-1 as a turn-on probe for amyloid beta (Aβ) species. Two-photon imaging indicates
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持