SML3101
MLi-2
≥98% (HPLC), selective leucine-rich repeat kinase 2 (LRRK2) inhibitor, powder
别名:
cis-2,6-Dimethyl-4-(6-(5-(1-methylcyclopropoxy)-1H-indazol-3-yl)pyrimidin-4-yl)morpholine, rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidinyl]-5-[(1-methylcyclopropyl)oxy]-1H-iIndazole
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关于此项目
经验公式（希尔记法）:
C21H25N5O2
化学文摘社编号:
分子量:
379.46
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
产品名称
MLi-2, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
C[C@]([H])(O[C@@]([H])(C1)C)CN1C2=CC(C3=NNC(C3=C4)=CC=C4OC5(C)CC5)=NC=N2
InChI key
ATUUNJCZCOMUKD-OKILXGFUSA-N
Biochem/physiol Actions
CNS active, highly potent and selective LRRK2 inhibitor
MLi-2 is an orally available, CNS active, highly potent and selective leucine-rich repeat kinase 2 (LRRK2) inhibitor. MLi-2 potently inhibits central and peripheral LRRK2 in mice.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable