SML3128
HU-308
≥95% (HPLC), CB2 cannabinoid receptor agonist
别名:
(1S,4S,5S)-4-[4-(1,1-Dimethylheptyl)-2,6-dimethoxyphenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-methanol, HU308
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关于此项目
经验公式（希尔记法）:
C27H42O3
化学文摘社编号:
分子量:
414.62
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
产品名称
HU-308, ≥95% (HPLC)
InChI
1S/C27H42O3/c1-8-9-10-11-12-26(2,3)19-14-23(29-6)25(24(15-19)30-7)20-13-18(17-28)21-16-22(20)27(21,4)5/h13-15,20-22,28H,8-12,16-17H2,1-7H3/t20-,21+,22-/m0/s1
SMILES string
CCCCCCC(C)(C1=CC(OC)=C(C(OC)=C1)[C@]2(C=C([C@@H]3C(C)([C@H]2C3)C)CO)[H])C
InChI key
CFMRIVODIXTERW-BDTNDASRSA-N
assay
≥95% (HPLC)
optical activity
[α]/D 180.0 to 130.0°, c = 0.5 in chloroform-d
storage condition
desiccated
color
white to dark beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−70°C
Quality Level
Biochem/physiol Actions
CB2 Cannabinoid receptor agonist
HU-308 is a potent, selective agonist of the cannabinoid receptor CB2. The Ki values for CB2 vs. CB1 are 22.7nM and >10 mM, respectively. HU-308 has anti-inflammatory and neuroprotective properties, and reduces liver damage in a hepatic ischemia/reperfusion injury model.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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