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Merck
CN

SML3170

QPD-Otf

≥98% (HPLC)

别名:

4-chloro-2-(6-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)phenyl trifluoromethanesulfonate

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关于此项目

经验公式(希尔记法):
C15H7Cl2F3N2O4S
化学文摘社编号:
分子量:
439.19
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

O=C1NC(C2=C(C=CC(Cl)=C2)OS(=O)(C(F)(F)F)=O)=NC3=CC=C(C=C31)Cl

Biochem/physiol Actions

QPD-OTf is a cell penetrant activity-based fluorogenic substrate for kinesin-1 that apparently binds to the nucleotide-binding site which removes triflate caging causing precipitation and crystallization of fluorescent QPD along microtubule cytoskeleton marking a kinesin-1 path from Golgi apparatus toward the cell periphery. QPD-OTf is not a substrate for Eg5.
cell penetrant activity-based fluorogenic substrate for kinesin-1


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号GTIN
SML3170-25MG04065267220239
SML3170-5MG04065267220246