QPD-Otf

Name: QPD-Otf
Brand: SIGMA

≥98% (HPLC)

别名:

4-chloro-2-(6-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)phenyl trifluoromethanesulfonate

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所有图片(1)

About This Item

经验公式（希尔记法）:

C₁₅H₇Cl₂F₃N₂O₄S

CAS Number:

2740660-92-6

分子量:

439.19

UNSPSC代码:

12352200

NACRES:

NA.77

质量水平

100

方案

≥98% (HPLC)

表单

powder

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear (warmed)

储存温度

2-8°C

SMILES字符串

O=C1NC(C2=C(C=CC(Cl)=C2)OS(=O)(C(F)(F)F)=O)=NC3=CC=C(C=C31)Cl

生化/生理作用

QPD-OTf is a cell penetrant activity-based fluorogenic substrate for kinesin-1 that apparently binds to the nucleotide-binding site which removes triflate caging causing precipitation and crystallization of fluorescent QPD along microtubule cytoskeleton marking a kinesin-1 path from Golgi apparatus toward the cell periphery. QPD-OTf is not a substrate for Eg5.

cell penetrant activity-based fluorogenic substrate for kinesin-1