SML3204
Dapansutrile
≥98% (HPLC)
别名:
3-(Methylsulfonyl)propanenitrile; 3-(Methylsulfonyl)propionitrile, Dapansutrile
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关于此项目
经验公式（希尔记法）:
C4H7NO2S
化学文摘社编号:
分子量:
133.17
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
O=S(C)(CCC#N)=O
InChI key
LQFRYKBDZNPJSW-UHFFFAOYSA-N
Biochem/physiol Actions
Dapansutrile is an orally active, specific and potent inhibitor of NLRP3 inflammasome activation that decreases IL-1β and IL-18 release. Dapansutrile exhibits no effect on NLRC4 and AIM2 inflammasomes activation. It appears that Dapansutrile directly interact with NLRP3. It does not show hematological, or organ toxicities in humans at oral doses up to 1,000 mg/day
orally active, specific and potent inhibitor of NLRP3 inflammasome activation; anti-inflammatory
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable