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SML3204

Dapansutrile

≥98% (HPLC)

别名:

3-(Methylsulfonyl)propanenitrile; 3-(Methylsulfonyl)propionitrile, Dapansutrile

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关于此项目

经验公式（希尔记法）:
C4H7NO2S
化学文摘社编号:
54863-37-5
分子量:
133.17
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD11934305
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O=S(C)(CCC#N)=O

InChI key

LQFRYKBDZNPJSW-UHFFFAOYSA-N

Biochem/physiol Actions

Dapansutrile is an orally active, specific and potent inhibitor of NLRP3 inflammasome activation that decreases IL-1β and IL-18 release. Dapansutrile exhibits no effect on NLRC4 and AIM2 inflammasomes activation. It appears that Dapansutrile directly interact with NLRP3. It does not show hematological, or organ toxicities in humans at oral doses up to 1,000 mg/day
orally active, specific and potent inhibitor of NLRP3 inflammasome activation; anti-inflammatory

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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