SML3208
CPYPP
≥98% (HPLC)
别名:
4-[3′-(2′′-chlorophenyl)-2′-propen-1′-ylidene]-1-phenyl-3,5-pyrazolidinedione
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关于此项目
经验公式（希尔记法）:
C18H13ClN2O2
化学文摘社编号:
分子量:
324.76
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
SMILES string
Clc1c(cccc1)C=CC=C2C(=O)N(NC2=O)c3ccccc3
InChI
1S/C18H13ClN2O2/c19-16-12-5-4-7-13(16)8-6-11-15-17(22)20-21(18(15)23)14-9-2-1-3-10-14/h1-12H,(H,20,22)
InChI key
VVZJFICTTKPNCK-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
orange to dark red
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
CPYPP is a cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain. CPYPP is a DOCK2-Rac1 interaction inhibitor. It also inhibits DOCK1 and DOCK5. CPYPP potently inhibits metastatic spread of aggressive ROBO1deficient prostate cancer cells through the vasculature of transgenic Zebrafish model.
cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain
存储类别
11 - Combustible Solids
wgk
WGK 3
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