SML3208
CPYPP
≥98% (HPLC)
别名:
4-[3′-(2′′-chlorophenyl)-2′-propen-1′-ylidene]-1-phenyl-3,5-pyrazolidinedione
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
orange to dark red
溶解性
DMSO: 2 mg/mL, clear
储存温度
−20°C
SMILES字符串
Clc1c(cccc1)C=CC=C2C(=O)N(NC2=O)c3ccccc3
InChI
1S/C18H13ClN2O2/c19-16-12-5-4-7-13(16)8-6-11-15-17(22)20-21(18(15)23)14-9-2-1-3-10-14/h1-12H,(H,20,22)
InChI key
VVZJFICTTKPNCK-UHFFFAOYSA-N
生化/生理作用
CPYPP is a cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain. CPYPP is a DOCK2-Rac1 interaction inhibitor. It also inhibits DOCK1 and DOCK5. CPYPP potently inhibits metastatic spread of aggressive ROBO1deficient prostate cancer cells through the vasculature of transgenic Zebrafish model.
cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain
储存分类代码
11 - Combustible Solids
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