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Merck
CN

SML3208

CPYPP

≥98% (HPLC)

别名:

4-[3′-(2′′-chlorophenyl)-2′-propen-1′-ylidene]-1-phenyl-3,5-pyrazolidinedione

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关于此项目

经验公式(希尔记法):
C18H13ClN2O2
化学文摘社编号:
分子量:
324.76
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

orange to dark red

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

Clc1c(cccc1)C=CC=C2C(=O)N(NC2=O)c3ccccc3

InChI

1S/C18H13ClN2O2/c19-16-12-5-4-7-13(16)8-6-11-15-17(22)20-21(18(15)23)14-9-2-1-3-10-14/h1-12H,(H,20,22)

InChI key

VVZJFICTTKPNCK-UHFFFAOYSA-N

Biochem/physiol Actions

CPYPP is a cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain. CPYPP is a DOCK2-Rac1 interaction inhibitor. It also inhibits DOCK1 and DOCK5. CPYPP potently inhibits metastatic spread of aggressive ROBO1deficient prostate cancer cells through the vasculature of transgenic Zebrafish model.
cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain


存储类别

11 - Combustible Solids

wgk

WGK 3



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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