SML3219
Tenofovir alafenamide
≥98% (HPLC), HIV and HBV reverse transcriptase inhibitor, powder
别名:
9-[(R)-2-[[(S)-[[(S)-1-(Isopropoxycarbonyl)ethyl]amino]phenoxyphosphinyl]-methoxy]-propyl]adenine, GS 7340, GS-7340, GS7340, TAF
登录 查看组织和合同定价。
选择规格
变更视图
关于此项目
经验公式（希尔记法）:
C21H29N6O5P
化学文摘社编号:
分子量:
476.47
NACRES:
NA.77
UNSPSC Code:
51111800
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
产品名称
Tenofovir alafenamide, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
CC(OC([C@@H](N[P@](CO[C@@H](CN1C2=NC=NC(N)=C2N=C1)C)(OC3=CC=CC=C3)=O)C)=O)C
InChI
1S/C21H29N6O5P/c1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27/h5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24)/t15-,16+,33+/m1/s1
InChI key
LDEKQSIMHVQZJK-CAQYMETFSA-N
Biochem/physiol Actions
HIV and HBV reverse transcriptase inhibitor tenofovir isopropylalaninyl phenyl ester with greater antiviral efficacy than tenofovir disoproxil fumarate.
Tenofovir alafenamide (TAF; GS-7340) is an isopropylalaninyl phenyl ester prodrug of the nucleotide analog reverse transcriptase inhibitor (nRTI) tenofovir (TFV) against human immunodeficiency virus (HIV) and hepatitis B virus (HBV). GS-7340 more efficiently delivers TFV into lymphoid cells and tissues than tenofovir disoproxil fumarate (TDF), resulting in greater antiviral efficacy against HIV.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable