SML3259
Morroniside
≥95% (HPLC)
别名:
[1S-(1α,3β,4aβ,8β,8aβ)]-8-(β-D-Glucopyranosyloxy)-4,4a,8,8a-tetrahydro-3-hydroxy-1-methyl-1H,3H-Pyrano[3,4-c]pyran-5-carboxylic Acid Methyl Ester, b-Morroniside
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关于此项目
经验公式（希尔记法）:
C17H26O11
化学文摘社编号:
分子量:
406.38
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
产品名称
Morroniside, ≥95% (HPLC)
SMILES string
O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@@H]2OC=C([C@@H]3[C@H]2[C@@H](OC(C3)O)C)C(=O)OC
InChI key
YTZSBJLNMIQROD-KKORFXOPSA-N
assay
≥95% (HPLC)
form
powder
color
white to beige
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
Bioactive natural product with antioxidant and anti-inflammatory activity
Morroniside is a bioactive natural product with antioxidant and anti-inflammatory activity. Its activities have included protecttion against cerebral ischemia/reperfusion injury by inhibiting neuron apoptosis and MMP2/9 expression and regulation of hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Guoyong Zeng et al.
Experimental and therapeutic medicine, 16(3), 2229-2234 (2018-09-07)
The aim of the present study was to investigate the effect of morroniside against matrix metalloproteinase (MMP)2/9 and focal cerebral ischemia/reperfusion (I/R) injury in rats. A rat model of focal cerebral I/R injury rats was established and rats were administered
Lijuan Zhou et al.
Scientific reports, 8(1), 13785-13785 (2018-09-15)
Hair loss is characterized by a shortened hair anagen phase and hair follicles (HF) miniaturization. Morroniside is the most abundant iridoid glycoside extracted from Cornus officinalis and has various bioactivities in different cell functions and tissue regeneration. In this study
Kang Chen et al.
European journal of pharmacology, 834, 295-304 (2018-07-31)
Amyloid-β peptide (Aβ) plays a causal role in the development and progression of Alzheimer's disease (AD). Oxidative stress and activation of mitogen-activated protein kinase (MAPK) are involved in Aβ-induced neurotoxicity. Morroniside, one active monomer of dry ripe sarcocarp of Cornus
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