SML3303
EU1622-1
≥98%
别名:
5-(4-chlorophenyl)-6-methyl-3-[2-oxo-2-(1-pyrrolidinyl)ethyl]-thieno[2,3-d]pyrimidin-4(3H)-one
质量水平
方案
≥98%
表单
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
CC1=C(C2=C(N=CN(C2=O)CC(N3CCCC3)=O)S1)C4=CC=C(C=C4)Cl
InChI
1S/C19H18ClN3O2S/c1-12-16(13-4-6-14(20)7-5-13)17-18(26-12)21-11-23(19(17)25)10-15(24)22-8-2-3-9-22/h4-7,11H,2-3,8-10H2,1H3
InChI key
KHRRGSKOOLJVDL-UHFFFAOYSA-N
生化/生理作用
EU1622-1 is pan-NMDAR (N-methyl d-aspartate receptors) positive allosteric modulator that decrease the conductance in all GluN2 NMDARs. EU1622-1 reduces calcium permeability. It has minimal effects on AMPA receptors.
pan-NMDAR (N-methyl d-aspartate receptors) PAM that decrease conductance and reduce calcium permeability
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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