InChI
1S/C17H23N5/c1-21-11-13-22(14-12-21)16-8-10-19-17(20-16)18-9-7-15-5-3-2-4-6-15/h2-6,8,10H,7,9,11-14H2,1H3,(H,18,19,20)
InChI key
BNXNWRSVYQHTOH-UHFFFAOYSA-N
SMILES string
CN1CCN(C2=CC=NC(NCCC3=CC=CC=C3)=N2)CC1
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Inactive control for TP-040 a brain penetrant, potent and selective inhibitor of O-GlcNAcase (OGA)
TP-040n is an inactive control for TP-040 a brain penetrant, potent and selective inhibitor of O-GlcNAcase (OGA).
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Michiko Tawada et al.
Journal of medicinal chemistry, 64(2), 1103-1115 (2021-01-07)
O-GlcNAcase (OGA) has received increasing attention as an attractive therapeutic target for tau-mediated neurodegenerative disorders; however, its role in these pathologies remains unclear. Therefore, potent chemical tools with favorable pharmacokinetic profiles are desirable to characterize this enzyme. Herein, we report
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