登录查看公司和协议定价
About This Item
经验公式（希尔记法）:
C24H33N4O9P
CAS Number:
分子量:
552.51
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77
生化/生理作用
PF-07304814 is a non-cytotoxic, aqueous soluble phosphate ester prodrug of the potent and selective corona virus inhibitor PF-00835231 (pro-/active drug SARS CoV-2 Ki = 174/0.27 nM). PF-07304814 is rapidly converted to PF-00835231, exhibiting anti-viral efficacy in cultures (PF-07304814/PF-00835231 IC50 with 2 μM P-pg efflux inhibitor CP-100356 = 3.8/0.24 μM (SARS2 Washington 1 & Vero E6-enACE2), 830/760 nM (SARS2 BetaCov GHB-03021/2020 & Vero E6-EGFP); PF-07304814/PF-00835231 IC50 with 0.5 μM CP-100356 = 58/80 nM (HCoV-229E & MRC-5)) without affecting P450 enzymes (>100 μM) or a range of transporters (>130 μM).
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持