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Merck
CN

SML3329

Decursinol Angelate

≥98% (HPLC), PKC activator, powder

别名:

(2Z)​-2-​Methyl-2-​butenoic acid (7S)​-​7,​8-​dihydro-​8,​8-​dimethyl-​2-​oxo-​2H,​6H-​benzo[1,​2-​b:5,​4-​b′]​dipyran-​7-​yl ester, Acutilobin

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关于此项目

经验公式(希尔记法):
C19H20O5
化学文摘社编号:
分子量:
328.36
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Form:
powder
Assay:
≥98% (HPLC)
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产品名称

Decursinol Angelate, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

[o]1c2c(cc3c(c2)OC([C@H](C3)OC(=O)\C(=C/C)\C)(C)C)cc[c]1=O

InChI

1S/C19H20O5/c1-5-11(2)18(21)23-16-9-13-8-12-6-7-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/b11-5-/t16-/m0/s1

InChI key

AGABNGOXUSXQDD-XKGFZTIGSA-N

Biochem/physiol Actions

Decursinol Angelate is a pyranocoumarin isolated from medical plant Angelica gigas that exhibits potent anti-inflammatory properties. Decursinol Angelate appears to suppress type 17 helper T (Th17) cell responses in dextran sodium sulfate-induced colitis model. Decursinol Angelate reduces the production of NF-κB and COX-2 induced proinflammatory cytokine levels on TPA induced mice ear edema.
Main anti-inflammatory component of Angelica gigas extract


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pictograms

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signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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