SML3331
Triheptanoin
≥95% (HPLC)
别名:
Dermofeel TC 7, Glycerol trienanthate, Glyceryl triheptanoate, Heptanoic acid, 1,1′,1′′-(1,2,3-propanetriyl) ester, Heptanoic acid, 1,2,3-propanetriyl ester (9CI), Heptanoin, tri- (6CI,7CI,8CI), Lanol 37T, Trienanthoin, Triheptanoic glyceride, Trioenanthoin, UX007
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关于此项目
经验公式（希尔记法）:
C24H44O6
化学文摘社编号:
分子量:
428.60
UNSPSC Code:
23201100
NACRES:
NA.77
MDL number:
Quality Level
assay
≥95% (HPLC)
form
oil
color
colorless to brown
storage temp.
−20°C
SMILES string
O(C(COC(=O)CCCCCC)COC(=O)CCCCCC)C(=O)CCCCCC
InChI
1S/C24H44O6/c1-4-7-10-13-16-22(25)28-19-21(30-24(27)18-15-12-9-6-3)20-29-23(26)17-14-11-8-5-2/h21H,4-20H2,1-3H3
InChI key
PJHKBYALYHRYSK-UHFFFAOYSA-N
Biochem/physiol Actions
Orally available triglyceride that provides 3 molar eq of saturated heptanoic acid in vivo to replenish reduced tricarboxylic acid (TCA; Krebs)-cycle intermediates.
Triheptanoin is a triglyceride with 3 molar eq. of saturated heptanoic acid (C7:0). The even-chain FA does not occur naturally and is able to bypass metabolic block induced by enzyme deficiency and to replenish reduced tricarboxylic acid/TCA-cycle (Krebs cycle or citric acid cycle/CAC) intermediates (anaplerosis) in vivo.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
404.6 °F - open cup
flash_point_c
207 °C - open cup
法规信息
新产品
此项目有
Keri J Fogle et al.
Molecular genetics and metabolism, 126(4), 439-447 (2019-01-27)
Seizures are a feature not only of the many forms of epilepsy, but also of global metabolic diseases such as mitochondrial encephalomyopathy (ME) and glycolytic enzymopathy (GE). Modern anti-epileptic drugs (AEDs) are successful in many cases, but some patients are
Ingrid Sofia Vieira de Melo et al.
Nutricion hospitalaria, 32(1), 265-269 (2015-08-12)
the aim of this study was to evaluate the influence of consumption of a ketogenic diet supplemented with triheptanoin, a medium-chain anaplerotic triacylglycerol, on the liver fatty acid profile of Wistar rats. three groups of male Wistar rats (n =
Sara Tucci et al.
Journal of lipid research, 58(1), 196-207 (2016-11-26)
A rather new approach in the treatment of long-chain fatty acid oxidation disorders is represented by triheptanoin, a triglyceride with three medium-odd-chain heptanoic acids (C7), due to its anaplerotic potential. We here investigate the effects of a 1-year triheptanoin-based diet
Tanya McDonald et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 40(3), 678-691 (2019-03-21)
Triheptanoin is anticonvulsant in several seizure models. Here, we investigated changes in glucose metabolism by triheptanoin interictally in the chronic stage of the pilocarpine mouse epilepsy model. After injection of [U-13C6]-glucose (i.p.), enrichments of 13C in intermediates of glycolysis and
Giovanna Testa et al.
Neuropharmacology, 148, 305-310 (2019-01-15)
The Forkhead Box G1 (FOXG1) gene encodes a transcription factor with an essential role in mammalian telencephalon development. FOXG1-related disorders, caused by deletions, intragenic mutations or duplications, are usually associated with severe intellectual disability, autistic features, and, in 87% of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML3331-10MG | 04065268085417 |
| SML3331-50MG | 04065268085424 |
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